Essential Evidence Plus

Essential Evidence Plus

Effect of timolol plus hydrochlorothiazide plus hydralazine on essential hypertension.

The effect on hypertension of hydrochlorothiazide 100 mg daily plus timolol 20-60 mg daily versus hydrochlorothiazide plus placebo and of hydrochlorothiazide plus timolol plus hydralazine 40-200 mg daily versus hydrochlorothiazide plus placebo plus hydralazine was evaluated in a double-blind, randomized, crossover study in 38 patients with hypertension. Hydrochlorothiazide plus timolol was more...

The NHS Plus evidence-based guideline project.

Over the past decade, evidence-based clinical guidelines (EBGs) have become an increasingly familiar part of medicine. The subsequent incorporation of evidence-based health care into every day practice has resulted in improvements in clinical effectiveness [1] as well as efficient allocation and utilization of health resources [2]. When NHS Plus was established in 2001, there appeared to be few...

Essential Evidence-Based Medicine Second Edition Essential Evidence-Based Medicine Second Edition

The abstract is a summary of the study. It should accurately reflect what actually happened in the study. Its purpose is to give you an overview of the research and let you decide if you want to read the full article. The abstract includes a sentence or two on each of the elements of the article. These include the introduction, study design, population studied, interventions and comparisons, ou...

Essential thrombocythaemia: challenges and evidence-based management.

Essential thrombocythaemia was first described over 70 years ago. This condition is dominated by thrombotic and haemorrhagic complications and, in the long-term, by risk of transformation to myelofibrosis and/or acute leukaemia. However, it is heterogeneous both clinically and biologically. Here, a review of current concepts in disease aetiology and management is offered with reference to recen...